Przejdź do zawartości
Merck

TNFSF12

tumor necrosis factor (ligand) superfamily, member 12

Synonimy:
APO3L, DR3LG, TWEAK
Gatunek:
Human TNFSF12 (8742), Mouse Tnfsf12 (21944), Rat Tnfsf12 (360548), domestic guinea pig Tnfsf12 (100713543), domestic cat TNFSF12 (101098755), Zebrafish tnfsf12 (567542), dog TNFSF12 (100568280), cow TNFSF12 (100568284), cow TNFSF12 (100551513), Domestic Rabbit TNFSF12 (100356651) ...Więcej
Identyfikator UniProtKB:
O43508, Q8IZK7, Q8WUZ7
Identyfikator genu:
  • Human(8742) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
  • Mouse(21944) tumor necrosis factor (ligand) superfamily, member 12
  • Rat(360548) tumor necrosis factor ligand superfamily member 12
  • domestic guinea pig(100713543) tumor necrosis factor (ligand) superfamily, member 12
  • domestic cat(101098755) tumor necrosis factor (ligand) superfamily, member 12
  • Zebrafish(567542) tumor necrosis factor (ligand) superfamily, member 12
  • dog(100568280) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100568284) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100551513) tumor necrosis factor (ligand) superfamily, member 12
  • Domestic Rabbit(100356651) tumor necrosis factor (ligand) superfamily, member 12
  • Horse(100061872) tumor necrosis factor (ligand) superfamily, member 12
  • sheep(101122801) tumor necrosis factor (ligand) superfamily, member 12

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Numer produktu
Opis
Gatunek
RAB0495
Mouse TWEAK ELISA Kit, for serum, plasma and cell culture supernatant,
Gatunek
mouse
RAB0749
Human TNFSF12 ELISA Kit, ,
Gatunek
human
RAB1765
Human TWEAK R ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB3500423
Anti-TWEAK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
WH0008742M1
Monoclonal Anti-TNFSF12 antibody produced in mouse, clone 4H3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
SAB4700906
Przeciwciało monoklonalne anty-CD255wytwarzane u myszy, clone CARL-1,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
HPA004863
Anti-TNFSF13 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
SAB1406716
Anti-TNFSF12 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Proteins

Numer produktu
Opis
Gatunek
GF102
TWEAK, human, Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU227381
MISSION® esiRNA, targeting human TNFSF12,
Gatunek
human
EHU097141
MISSION® esiRNA, targeting human TNFSF12-TNFSF13, TNFSF13,
Gatunek
human