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PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Synonimy:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

Numer produktu
Opis
Gatunek
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-COX2/PTGS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, pig, sheep
Zastosowanie
ELISA
flow cytometry

immunofluorescence

western blot
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cox2 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-COX2, C-Terminal Rabbit pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
bovine, human, mouse, rat, sheep
Zastosowanie

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Aceclofenac, ≥98% (HPLC),
Gatunek
human
Valdecoxib, ≥98% (HPLC),
Gatunek
human
Celecoxib, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Carprofen for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Celecoxib, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Ptgs2,
Gatunek
mouse
MISSION® esiRNA, targeting human PTGS2,
Gatunek
human