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Merck

PRPH2

peripherin 2 (retinal degeneration, slow)

Synonimy:
AOFMD, AVMD, CACD2, DS, PRPH, RDS, RP7, TSPAN22, rd2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5961) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. [provided by RefSeq, Jul 2008]
  • Mouse(19133) peripherin 2
  • Rat(25534) peripherin 2
  • domestic cat(727697) peripherin 2 (retinal degeneration, slow)
  • sheep(101109569) peripherin 2 (retinal degeneration, slow)
  • cow(280907) peripherin 2 (retinal degeneration, slow)
  • chicken(395899) peripherin 2 (retinal degeneration, slow)
  • naked mole-rat(101702401) peripherin 2 (retinal degeneration, slow)
  • dog(403972) peripherin 2 (retinal degeneration, slow)
  • domestic guinea pig(100713395) peripherin 2 (retinal degeneration, slow)

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PRPH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-Peripherin Antibody, serum, Chemicon®,
Reaktywność gatunkowa
bovine, human, mouse, pig, rat
Zastosowanie
immunohistochemistry
western blot
Anti-Peripherin-2 Antibody, clone 2B7, clone 2B7, from mouse,
Reaktywność gatunkowa
bovine, mouse
Zastosowanie
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-Peripherin-2 Antibody, clone 6B10.1, clone 6B10.1, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-Peripherin-2, klon 5H2, clone 5H2, from mouse,
Reaktywność gatunkowa
bovine, mouse
Zastosowanie
immunofluorescence
radioimmunoassay

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PRPH2,
Gatunek
human