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Merck

POLK

polymerase (DNA directed) kappa

Synonimy:
DINB1, DINP, POLQ
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(51426) Summary: External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007 [PubMed 17317631]
  • Mouse(27015) polymerase (DNA directed), kappa
  • Rat(171525) polymerase (DNA directed) kappa
  • domestic guinea pig(100726233) polymerase (DNA directed) kappa
  • naked mole-rat(101718580) polymerase (DNA directed) kappa
  • sheep(101109360) polymerase (DNA directed) kappa
  • Domestic Rabbit(100352218) polymerase (DNA directed) kappa
  • Zebrafish(562749) polymerase (DNA directed) kappa
  • domestic cat(101099613) polymerase (DNA directed) kappa
  • cow(541218) polymerase (DNA directed) kappa
  • dog(479180) polymerase (DNA directed) kappa
  • chicken(374003) polymerase (DNA directed) kappa
  • Horse(100065534) polymerase (DNA directed) kappa

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-POLK antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human, mouse, pig, rat
Zastosowanie
western blot
Anti-POLK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Monoclonal Anti-POLK antibody produced in mouse, clone 4F12, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunoprecipitation (IP)

western blot
Monoclonal Anti-POLK antibody produced in mouse, clone 6F2, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-POLK, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Polk,
Gatunek
mouse
MISSION® esiRNA, targeting human POLK,
Gatunek
human