Przejdź do zawartości
Merck

PDK1

pyruvate dehydrogenase kinase, isozyme 1

Synonimy:
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
  • Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
  • Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
  • fruit fly(38017) Phosphoinositide-dependent kinase 1
  • Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
  • Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
  • Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
  • domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1
  • naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
  • sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
  • Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
  • cow(528655) pyruvate dehydrogenase kinase, isozyme 1
  • domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
  • dog(476828) pyruvate dehydrogenase kinase, isozyme 1
  • chicken(425972) pyruvate dehydrogenase kinase, isozyme 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

Numer produktu
Opis
Gatunek
Dichloroacetic acid, ReagentPlus®, ≥99%,
Gatunek
human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-PDK1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PDH kinase 1 Antibody, clone 1C7-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Przeciwciało anty-PDK1/PDHK1, klon 5T6S8, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Dichloroacetic acid, ReagentPlus®, ≥99%,
Gatunek
human, rat
Sodium dichloroacetate, 98%,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
PDHK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PDK1,
Gatunek
human
MISSION® esiRNA, targeting mouse Pdk1,
Gatunek
mouse