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Merck

PDE3A

phosphodiesterase 3A, cGMP-inhibited

Synonimy:
CGI-PDE, CGI-PDE A, CGI-PDE-A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5139) Summary: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(54611) phosphodiesterase 3A, cGMP inhibited
  • Rat(50678) phosphodiesterase 3A, cGMP inhibited
  • domestic cat(101088586) phosphodiesterase 3A, cGMP-inhibited
  • naked mole-rat(101704787) phosphodiesterase 3A, cGMP-inhibited
  • Domestic Rabbit(100009330) phosphodiesterase 3A, cGMP-inhibited
  • Horse(100034086) phosphodiesterase 3A, cGMP-inhibited
  • sheep(101115870) phosphodiesterase 3A, cGMP-inhibited
  • Zebrafish(567051) phosphodiesterase 3A, cGMP-inhibited
  • cow(536636) phosphodiesterase 3A, cGMP-inhibited
  • chicken(418185) phosphodiesterase 3A, cGMP-inhibited
  • domestic guinea pig(100302667) phosphodiesterase 3A, cGMP inhibited

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-PDE3A antibody produced in mouse, clone 5C12, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-PDE3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anty-PDE3A, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Cilostazol, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Cilostazol, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Amrinone, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Milrinone, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Cilostazol, ≥98% (HPLC), powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human PDE3A,
Gatunek
human
MISSION® esiRNA, targeting mouse Pde3a,
Gatunek
mouse