KLHL3
kelch-like family member 3
Synonimy:
PHA2D
Gatunek:
Human KLHL3 (26249), Mouse Klhl3 (100503085), Rat Klhl3 (498697), domestic guinea pig Klhl3 (100732587), naked mole-rat Klhl3 (101699865), sheep KLHL3 (101107091), Horse KLHL3 (100062564), cow KLHL3 (533364), Domestic Rabbit KLHL3 (100343290), domestic cat KLHL3 (101083647) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(26249) Summary: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
- Mouse(100503085) kelch-like 3
- Rat(498697) kelch-like family member 3
- domestic guinea pig(100732587) kelch-like family member 3
- naked mole-rat(101699865) kelch-like family member 3
- sheep(101107091) kelch-like 3 (Drosophila)
- Horse(100062564) kelch-like 3 (Drosophila)
- cow(533364) kelch-like family member 3
- Domestic Rabbit(100343290) kelch-like 3 (Drosophila)
- domestic cat(101083647) kelch-like 3 (Drosophila)
- Zebrafish(568556) kelch-like 3 (Drosophila)
- chicken(416303) kelch-like 3 (Drosophila)
- dog(481523) kelch-like 3 (Drosophila)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-KLHL3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-KLHL3 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rat
Zastosowanie
western blot
Anti-KLHL3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-KLHL3 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human, rabbit
Zastosowanie
western blot
esiRNA
Numer produktu
Opis
Gatunek