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HRH1

histamine receptor H1

Synonimy:
H1-R, hisH1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3269) Summary: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be intronless until recently. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15465) histamine receptor H1
  • Rat(24448) histamine receptor H 1
  • naked mole-rat(101715481) histamine receptor H1
  • domestic cat(101088314) histamine receptor H1
  • domestic guinea pig(100135539) histamine receptor H1
  • chicken(100858928) histamine receptor H1
  • domestic guinea pig(100730517) histamine receptor H1
  • cow(281231) histamine receptor H1
  • dog(403813) histamine receptor H1
  • Zebrafish(735302) histamine receptor H1
  • Horse(100034110) histamine receptor H1
  • sheep(101121717) histamine receptor H1

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Histamine, analytical standard,
Gatunek
human
Histamine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Histamine dihydrochloride, ≥99.0% (AT),
Gatunek
human
Histamine dihydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Histamine dihydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Dimenhydrinate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Doxylamine hydrogen succinate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Desloratadine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Loratadine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Ketotifen for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-HRH1 antibody produced in mouse, clone 3D1, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
Anti-Histamine Receptor 1 Antibody, CT, Chemicon®, from rabbit,
Reaktywność gatunkowa
bovine, mouse, rat
Zastosowanie
ELISA
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Cinnarizine, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Mianserin hydrochloride, ,
Gatunek
human
Cinnarizine, powder,
Gatunek
human
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Ketotifen fumarate salt, ,
Gatunek
human
L-Histidinol dihydrochloride, ≥98 (TLC),
Gatunek
mouse, rat, human
D-Histidine monohydrochloride monohydrate, ≥98% (TLC),
Gatunek
mouse, rat, human
Loratadine, ≥98% (HPLC), powder,
Gatunek
rat, human
Histamine, ≥97.0%,
Gatunek
human, rat

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Loratadine, ≥98% (HPLC), powder,
Gatunek
rat, human
Cinnarizine, powder,
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
1-Methylhistamine dihydrochloride, ≥98% (TLC), powder,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
Haloperidol, powder,
Gatunek
human, rat
Clozapine, ,
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human HRH1,
Gatunek
human
MISSION® esiRNA, targeting mouse Hrh1,
Gatunek
mouse