HRAS
Harvey rat sarcoma viral oncogene homolog
Synonimy:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Gatunek:
Human HRAS (3265), Rat Hras (293621), dog HRAS (403735), cow HRAS (100298939), naked mole-rat Hras (101716053), chicken HRAS (396229), domestic guinea pig Hras (100735038), sheep HRAS (101104357)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
- Rat(293621) Harvey rat sarcoma virus oncogene
- dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
- sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
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Custom Gene Products
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Small Molecule - Antagonist
Numer produktu
Opis
Gatunek
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Gatunek
human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-HRAS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
proximity ligation assay
western blot
western blot
Anti-RASH antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anty-HRAS, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-H-Ras, klon 7D7.2, clone 7D7.2, Chemicon®, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anty-HRAS, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
esiRNA
Numer produktu
Opis
Gatunek