Przejdź do zawartości
Merck

HARS

histidyl-tRNA synthetase

Synonimy:
HRS, USH3B
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3035) Summary: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(15115) histidyl-tRNA synthetase
  • Rat(307492) histidyl-tRNA synthetase
  • naked mole-rat(101712452) histidyl-tRNA synthetase
  • cow(510937) histidyl-tRNA synthetase
  • domestic guinea pig(100729679) histidyl-tRNA synthetase
  • dog(478034) histidyl-tRNA synthetase
  • sheep(101120491) histidyl-tRNA synthetase
  • chicken(416132) histidyl-tRNA synthetase
  • Domestic Rabbit(100351394) histidyl-tRNA synthetase
  • domestic cat(101097371) histidyl-tRNA synthetase
  • Zebrafish(447847) histidyl-tRNA synthetase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-HARS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-HARS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot

Proteins

Numer produktu
Opis
Gatunek
Jo-1 human, recombinant, expressed in E. coli, solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Hars,
Gatunek
mouse
MISSION® esiRNA, targeting human HARS,
Gatunek
human