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Merck

F3

coagulation factor III (thromboplastin, tissue factor)

Synonimy:
CD142, TF, TFA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2152) Summary: This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(14066) coagulation factor III
  • Rat(25584) coagulation factor III (thromboplastin, tissue factor)
  • naked mole-rat(101702267) coagulation factor III (thromboplastin, tissue factor)
  • domestic guinea pig(100135463) coagulation factor III
  • Domestic Rabbit(100009127) coagulation factor III (thromboplastin, tissue factor)
  • sheep(101118918) coagulation factor III (thromboplastin, tissue factor)
  • cow(280686) coagulation factor III
  • domestic cat(101082330) coagulation factor III (thromboplastin, tissue factor)
  • dog(490153) coagulation factor III (thromboplastin, tissue factor)
  • chicken(429084) coagulation factor III (thromboplastin, tissue factor)

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ELISA

Numer produktu
Opis
Gatunek
MouseCoagulation Factor III ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
mouse
Human F3 / Tissue Factor ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CD142 PE produced in mouse, ,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Anti-F3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-phospho-Coagulation Factor III (pSer290) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-F3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
Anti-Tissue Factor Antibody, clone 2L10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Proteins

Numer produktu
Opis
Gatunek
Thromboplastin from rabbit, ,
Gatunek
domestic rabbit

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human F3,
Gatunek
human