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Merck

CA11

carbonic anhydrase XI

Synonimy:
CARPX1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(770) Summary: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq, Jul 2008]
  • domestic guinea pig(100730055) carbonic anhydrase XI
  • dog(484400) carbonic anhydrase XI
  • sheep(443426) carbonic anhydrase XI
  • cow(326334) carbonic anhydrase XI
  • domestic cat(101081097) carbonic anhydrase XI
  • naked mole-rat(101719709) carbonic anhydrase XI

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Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Hydrochlorothiazide, crystalline,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CA11,
Gatunek
human