Przejdź do zawartości
Merck

ANPEP

alanyl (membrane) aminopeptidase

Synonimy:
APN, CD13, GP150, LAP1, P150, PEPN
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Numer produktu
Opis
Gatunek
Ludzka aminopeptydaza N ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, nonhuman primates
Zastosowanie
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-APN/CD13 Antibody, clone BR2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry

immunocytochemistry
Anti-APN/CD13 Antibody, clone 1D20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anty-CD13/ANPEP, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-ANPEPwytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine, 97%,
Gatunek
human, mouse, rat
Actinonin, ,
Gatunek
human
Flavone, ≥99.0%,
Gatunek
human, rat, mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Anpep,
Gatunek
mouse
MISSION® esiRNA, targeting human ANPEP,
Gatunek
human