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  • Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.

Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor.

Nature (1989-04-13)
F Ishikawa, K Miyazono, U Hellman, H Drexler, C Wernstedt, K Hagiwara, K Usuki, F Takaku, W Risau, C H Heldin
ABSTRACT

Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell growth factor indicates that it is a novel factor distinct from previously characterized proteins. The factor, a protein with a relative molecular mass of about 45,000, stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Thymidine Phosphorylase, recombinant from Escherichia coli, recombinant, expressed in E. coli, buffered aqueous solution, ≥900 units/mL, 0.2 μm filtered
Sigma-Aldrich
Thymidine Phosphorylase, recombinant from Escherichia coli, recombinant, expressed in E. coli, buffered aqueous solution, ≥500 units/mL