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EMU004041

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Galnt1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGGACAGGGCAGATTATCAATAAGAATAACAGGCGGCTTGCAGAAGTATGGATGGATGAATTCAAGAATTTCTTCTATATAATTTCTCCAGGTGTTACAAAGGTAGATTATGGAGATATATCATCAAGACTTGGCCTAAGACGTAAACTACAATGCAAACCTTTCTCTTGGTACCTAGAAAATATTTACCCTGATTCTCAAATTCCTCGTCACTATTTCTCATTGGGAGAGATACGAAATGTGGAAACAAATCAGTGTCTAGATAACATGGCTAGAAAAGAGAATGAAAAGGTTGGAATCTTTAATTGTCATGGTATGGGAGGTAATCAGGTTTTCTCCTACACTGCCAACAAAGAAATTAGAACAGACGACCTTTGTTTGGACGTTTCCAAACTTAATGGCCCAG

Ensembl | mouse accession no.

ENSMUSG00000000420

NCBI accession no.

NM_013814

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... GALNT1(14423) , Galnt1(14423)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Miao-Juei Huang et al.
Oncotarget, 6(8), 5650-5665 (2015-03-03)
O-glycosylation is a common protein modification. Aberrant O-glycosylation is associated with many cancers. GALNT1 is a GalNAc-transferase that initiates protein O-glycosylation. We found that GALNT1 is frequently up-regulated in hepatocellular carcinoma (HCC) and is associated with poor patient survival. Overexpression

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