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C5112

Sigma-Aldrich

Monoclonal Anti-CUG-BP1 antibody produced in mouse

clone HL 1190 (3B1-3D11), purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-hNab50

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About This Item

MDL number:
MFCD03792416
UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

HL 1190 (3B1-3D11), monoclonal

form

buffered aqueous solution

species reactivity

pig, human, mouse, rat, rabbit, bovine

technique(s)

immunocytochemistry: suitable
microarray: suitable
western blot: 0.25 μg/mL using extract of C-2 (mouse myoblasts) cells

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... CUGBP1(10658)
mouse ... Cugbp1(13046)
rat ... Cugbp1(362160)

Immunogen

human CUG-BP1 (nuclear RNA binding protein).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Chang Jiang et al.
Cell reports, 28(5), 1307-1322 (2019-08-01)
CD40 has major roles in B cell development, activation, and germinal center responses. CD40 hypoactivity causes immunodeficiency whereas its overexpression causes autoimmunity and lymphomagenesis. To systematically identify B cell autonomous CD40 regulators, we use CRISPR/Cas9 genome-scale screens in Daudi B

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