43713

S-(5′-Adenosyl)-3-thiopropylamine

≥98.0% (HPLC), powder

• Synonym(s): 5′-[(3-Aminopropyl)thio]-5′-deoxyadenosine, S-Adenosyl-3-thiopropylamine, dc-SAH, dcAdoHcy, decarboxylated S-Adenosyl-L-homocysteine
• Empirical Formula (Hill Notation): C₁₃H₂₀N₆O₃S
• CAS Number: 53186-57-5
• Molecular Weight: 340.40
• UNSPSC Code: 12352204
• PubChem Substance ID: 329756367
• NACRES: NA.32
• MDL number: MFCD17215932

Properties

• Product Name: S-(5′-Adenosyl)-3-thiopropylamine, ≥98.0% (HPLC)
• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: NCCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23
• InChI: 1S/C13H20N6O3S/c14-2-1-3-23-4-7-9(20)10(21)13(22-7)19-6-18-8-11(15)16-5-17-12(8)19/h5-7,9-10,13,20-21H,1-4,14H2,(H2,15,16,17)/t7-,9-,10-,13-/m1/s1
• InChI key: FUSRAALGPJJIRO-QYVSTXNMSA-N

Description

Application

S-(5′-Adenosyl)-3-thiopropylamine has been used as a calibrant solution to spike human urine samples for solid-phase extraction studies. It has also been used as an analyte in capillary electrophoresis (CE) and micellar electrokinetic chromatography (MEKC).[1]

Biochem/physiol Actions

S-(5′-Adenosyl)-3-thiopropylamine or S-adenosyl-L-homocysteine comprises base, sugar or amino acid. It acts as an inhibitor for spermidine synthase and spermine synthase.[2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This decarboxylated S-Adenosyl-L-methionine is an important metabolite in polyamine biosynthesis, acting as aminopropyl group donor for propylamine transferases such as spermine synthase and spermidine synthase.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H300
• pcodes: P264 - P301 + P310
• Hazard Classifications: Acute Tox. 2 Oral
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges