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32553

Supelco

Tinidazole

VETRANAL®, analytical standard

Synonym(s):

1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C8H13N3O4S
CAS Number:
19387-91-8
Molecular Weight:
247.27
Beilstein:
618182
EC Number:
243-014-4
MDL number:
MFCD00057217
UNSPSC Code:
41116107
PubChem Substance ID:
329754026
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCS(=O)(=O)CCn1c(C)ncc1[N+]([O-])=O

InChI

1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3

InChI key

HJLSLZFTEKNLFI-UHFFFAOYSA-N

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General description

Tinidazole belongs to the family of nitroimidazole compounds.[1]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tinidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Tablet formulations[2] and human serum samples[3] by reversed phase-high performance liquid chromatography (RP-HPLC).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H312 + H332,H341,H351

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2 - Muta. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3896
BCCC5372
BCBZ8493
BCBV9140

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Simultaneous estimation of ciprofloxacin hydrochloride, ofloxacin, tinidazole and ornidazole by reverse phase-high performance liquid chromatography.
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Helicobacter pylori have become resistant to antimicrobial agents, reducing eradication rates. A 10-day sequential regimen that contains levofloxacin was efficient, safe, and cost saving in eradicating H pylori infection in an area with high prevalence of clarithromycin resistance. We performed
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Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 96, 259-270 (2012-06-12)
Three simple, specific, accurate and precise spectrophotometric methods manipulating ratio spectra are developed for simultaneous determination of omeprazole (OM), tinidazole (TN) and clarithromycin (CL) in tablets. Method A, is an extended ratio subtraction one (EXRSM). Method B is a ratio
Elizabeth A Bosserman et al.
Sexually transmitted diseases, 38(10), 983-987 (2011-09-22)
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of
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