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513067

Sigma-Aldrich

2-Hydroxychalcone

95%

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About This Item

Linear Formula:
HOC6H4CH=CHCOC6H5
CAS Number:
Molecular Weight:
224.25
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

95%

mp

144-150 °C (lit.)

SMILES string

Oc1ccccc1\C=C\C(=O)c2ccccc2

InChI

1S/C15H12O2/c16-14-9-5-4-8-13(14)10-11-15(17)12-6-2-1-3-7-12/h1-11,16H/b11-10+

InChI key

UDOOPSJCRMKSGL-ZHACJKMWSA-N

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Cesar Echeverria et al.
International journal of molecular sciences, 10(1), 221-231 (2009-04-01)
Relationships between the structural characteristic of synthetic chalcones and their antitumoral activity were studied. Treatment of HepG2 cells for 24 h with synthetic 2'-hydroxychalcones resulted in apoptosis induction and dose-dependent inhibition of cell proliferation. The calculated reactivity indexes and the
Kunan Bangphumi et al.
European journal of drug metabolism and pharmacokinetics, 41(6), 777-785 (2015-11-14)
Curcumin is the major bioactive component of turmeric, but has poor oral bioavailability that limits its clinical applications. To improve the in vitro solubility and alkaline stability, we developed a prodrug of curcumin by succinylation to obtain curcumin diethyl disuccinate
Beata Żyszka-Haberecht et al.
Journal of biotechnology, 293, 36-46 (2019-01-29)
Halophilic and freshwater strains of cyanobacteria representing the Oscillatoriales, Nostocales, Chroococcales, and Synechococcales orders of Cyanophyta were examined to determine (i) the resistance of their cultures when suppressed by the presence of exogenous methoxylated and methylated derivatives of 2'-hydroxychalcone, (ii)

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