Skip to Content
Merck

P4HA1

prolyl 4-hydroxylase, alpha polypeptide I

Synonyms:
P4HA
Species:
UniProtKB ID:
Gene ID:
  • Human(5033) Summary: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(18451) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
  • Rat(64475) prolyl 4-hydroxylase, alpha polypeptide I
  • Domestic Rabbit(100340270) prolyl 4-hydroxylase, alpha polypeptide I
  • naked mole-rat(101702867) prolyl 4-hydroxylase, alpha polypeptide I
  • chicken(423704) prolyl 4-hydroxylase, alpha polypeptide I
  • domestic guinea pig(100716746) prolyl 4-hydroxylase, alpha polypeptide I
  • sheep(101116374) prolyl 4-hydroxylase, alpha polypeptide I
  • dog(479242) prolyl 4-hydroxylase, alpha polypeptide I
  • domestic cat(101096846) prolyl 4-hydroxylase, alpha polypeptide I
  • cow(518288) prolyl 4-hydroxylase, alpha polypeptide I

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-P4HA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-P4HA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-P4HA1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-P4HA1 Antibody, clone 1C14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human P4HA1,
Species
human
MISSION® esiRNA, targeting mouse P4ha1,
Species
mouse