GP1BA
glycoprotein Ib (platelet), alpha polypeptide
Synonyms:
BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP
Species:
Human GP1BA (2811), Mouse Gp1ba (14723), Rat Gp1ba (691992), chicken GP1BA (420059), naked mole-rat Gp1ba (101717127), domestic guinea pig Gp1ba (100717535), sheep GP1BA (101109891), cow GP1BA (504977), domestic cat GP1BA (101092307), dog GP1BA (403638)
UniProtKB ID:
Gene ID:
- Human(2811) Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010]
- Mouse(14723) glycoprotein 1b, alpha polypeptide
- Rat(691992) glycoprotein Ib (platelet), alpha polypeptide
- chicken(420059) glycoprotein Ib (platelet), alpha polypeptide
- naked mole-rat(101717127) glycoprotein Ib (platelet), alpha polypeptide
- domestic guinea pig(100717535) glycoprotein Ib (platelet), alpha polypeptide
- sheep(101109891) glycoprotein Ib (platelet), alpha polypeptide
- cow(504977) glycoprotein Ib (platelet), alpha polypeptide
- domestic cat(101092307) glycoprotein Ib (platelet), alpha polypeptide
- dog(403638) glycoprotein Ib (platelet), alpha polypeptide
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CD42b antibody produced in mouse, clone HIP1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, nonhuman primates
Application
flow cytometry
Anti-GP1BA antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-GP1BA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CD42b/GP1BA Antibody, clone 1C9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
affinity binding assay
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-CD42b antibody produced in mouse, clone AK2,
Species Reactivity
human
Application
flow cytometry