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Merck

CAMK2B

calcium/calmodulin-dependent protein kinase II beta

Synonyms:
CAM2, CAMK2, CAMKB
Species:
UniProtKB ID:
Gene ID:
  • Human(816) Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12323) calcium/calmodulin-dependent protein kinase II, beta
  • Rat(24245) calcium/calmodulin-dependent protein kinase II beta
  • cow(525416) calcium/calmodulin-dependent protein kinase II beta
  • Horse(100146368) calcium/calmodulin-dependent protein kinase II beta
  • domestic cat(101098615) calcium/calmodulin-dependent protein kinase II beta
  • chicken(374174) calcium/calmodulin-dependent protein kinase II beta
  • dog(608846) calcium/calmodulin-dependent protein kinase II beta
  • naked mole-rat(101718749) calcium/calmodulin-dependent protein kinase II beta
  • domestic guinea pig(100717077) calcium/calmodulin-dependent protein kinase II beta
  • sheep(101118870) calcium/calmodulin-dependent protein kinase II beta

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Small Molecule - Antagonist

Product Number
Description
Species
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CaM Kinase II β Antibody, clone 1F13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse, rat
Application
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-CaMK2-β/γ/δ (pThr287) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-CaMKII Antibody, clone 7L9F0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-CAMK2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Anti-CAMK2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Calmodulin-dependent Protein Kinase II fragment 290-309, ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CAMK2B,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Species
mouse, rat, human