- Anxiolytic and antidepressant effects of aqueous tincture of the aerial part of Myosotis arvensis.
Anxiolytic and antidepressant effects of aqueous tincture of the aerial part of Myosotis arvensis.
Bulletin of experimental biology and medicine (2012-03-31)
N Yu Polomeyeva, R V Gurto, O S Bryushinina, V A Slepichev, A V Kaigorodtsev, V Yu Smirnov, N I Suslov, V V Udut
PMID22462056
ABSTRACT
Experiments on outbred albino mice showed a significant anxiolytic effect of aqueous tincture of the aerial part of Myosotis arvensis (L.) (Boraginaceae) in a single daily dose of 0.5 ml/kg. In a dose of 2 ml/kg, the tincture of M. arvensis aerial part exhibited an anxiolytic and antidepressant effect. In contrast to phenazepam, aqueous tincture of M. arvensis did not inhibit exploratory and motor activities.
MATERIALS
Product Number
Brand
Product Description
Supelco
Phenazepam solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®