240907

Trimethyl phosphite

≥99%

• Synonym(s): Methyl phosphite, P(OMe)₃, Trimethoxyphosphine
• Linear Formula: (CH₃O)₃P
• CAS Number: 121-45-9
• Molecular Weight: 124.08
• Beilstein: 956570
• EC Number: 204-471-5
• MDL number: MFCD00008350
• UNSPSC Code: 12352108
• PubChem Substance ID: 24854442
• NACRES: NA.22

Properties

• vapor density: 4.3 (vs air)
• Quality Level: 200
• vapor pressure: 17 mmHg ( 20 °C)
• Assay: ≥99%
• form: liquid
• reaction suitability: reagent type: ligand; reaction type: Heck Reaction; reagent type: ligand; reaction type: Suzuki-Miyaura Coupling
• refractive index: n20/D 1.408 (lit.)
• bp: 111-112 °C (lit.)
• mp: −78 °C (lit.)
• density: 1.052 g/mL at 25 °C (lit.)
• SMILES string: COP(OC)OC
• InChI: 1S/C3H9O3P/c1-4-7(5-2)6-3/h1-3H3
• InChI key: CYTQBVOFDCPGCX-UHFFFAOYSA-N

Description

General description

Trimethyl phosphite is an organophosphorus compound commonly used as a polymerization catalyst, coating additive, and as an intermediate in the synthesis of flame retardants. In addition, it is also used as an activating reagent in amide formation.

Application

Trimethyl phosphite can be used as a ligand in the synthesis of allyliridium phosphite complexes by direct reaction with allyliridium 1,5-cyclooctadiene complex.

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H302,H315,H319,H335
• Precautionary Statements: P210 - P233 - P240 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Supplementary Hazards: EUH014
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point(F): 82.4 °F - closed cup
• Flash Point(C): 28 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves