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  • Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development.

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development.

Frontiers in immunology (2018-02-07)
Diahann T S L Jansen, Nishta Ramnoruth, Khai L Loh, Jamie Rossjohn, Hugh H Reid, Hendrik J Nel, Ranjeny Thomas
PMID29403492
ABSTRACT

With the advent of novel strategies to induce tolerance in autoimmune and autoimmune-like conditions, clinical trials of antigen-specific tolerizing immunotherapy have become a reality. Besides safety, it will be essential to gather mechanistic data on responding CD4