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  • Multiple deprotonations and deaminations of phenethylamines to synthesize pyrroles.

Multiple deprotonations and deaminations of phenethylamines to synthesize pyrroles.

Journal of the American Chemical Society (2006-09-14)
Xiaobing Wan, Dong Xing, Zhao Fang, Bijie Li, Fei Zhao, Keya Zhang, Liping Yang, Zhangjie Shi
ABSTRACT

A unique method was discovered to construct polysubstituted pyrroles via an unprecedented multiple deprotonations/deaminations process from commercially available phenethylamines. During this transformation, twelve bonds were broken and five new bonds were constructed.

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Sigma-Aldrich
Palladium(II) chloride, ReagentPlus®, 99%