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  • Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.

Direct amination of α-substituted nitroacetates using di-tert-butyl azodicarboxylate catalyzed by Hatakeyama's catalyst β-ICD.

Organic & biomolecular chemistry (2012-01-11)
Cong-Bin Ji, Yun-Lin Liu, Xiao-Li Zhao, Yin-Long Guo, Hao-Yang Wang, Jian Zhou
PMID22231285
ABSTRACT

We report the first example of catalytic asymmetric direct amination of α-monosubstituted nitroacetates using di-tert-butyl azodicarboxylate. The simple and easily available Hatakeyama's catalyst β-ICD 11 was found to be a highly enantioselective catalyst for this reaction.