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  • Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions.

Chemical and microbiologic characteristics and toxicity of povidone-iodine solutions.

American journal of surgery (1986-03-01)
J L Zamora
ABSTRACT

The chemical, microbiologic, and toxic characteristics of povidone-iodine solution, a commonly used antiseptic agent, are addressed in a collective review of relevant works published from 1956 to the present. Interactions of this agent with the thyroid gland and the kidneys and its toxicity at the cellular and systemic level are discussed.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Polyvinylpyrrolidone, nucleic acid hybridization tested, mol wt 360,000
Sigma-Aldrich
Polyvinylpyrrolidone, average mol wt 40,000
Sigma-Aldrich
Polyvinylpyrrolidone, average mol wt 10,000
Supelco
Poly(vinylpolypyrrolidone), ~110 μm particle size
Povidone, European Pharmacopoeia (EP) Reference Standard
USP
Crospovidone, United States Pharmacopeia (USP) Reference Standard
Crospovidone, European Pharmacopoeia (EP) Reference Standard
Supelco
Povidone, Pharmaceutical Secondary Standard; Certified Reference Material
USP
Povidone, United States Pharmacopeia (USP) Reference Standard