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  • Copper-catalyzed oxidative decarboxylative couplings of sulfoximines and aryl propiolic acids.

Copper-catalyzed oxidative decarboxylative couplings of sulfoximines and aryl propiolic acids.

Organic letters (2013-11-28)
Daniel L Priebbenow, Peter Becker, Carsten Bolm
ABSTRACT

A method has been developed for the preparation of N-alkynylated sulfoximines involving the copper-catalyzed decarboxylative coupling of sulfoximines with aryl propiolic acids. A range of substituents on both the sulfoximidoyl moiety and the aryl group of the propiolic acid were compatible with this reaction process to afford a series of sulfoximidoyl-functionalized alkynes.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Copper, wire, diam. 1.0 mm, ≥99.9%
Sigma-Aldrich
Copper, wire, diam. 2.0 mm, 99.999% trace metals basis
Sigma-Aldrich
Copper, wire, diam. 0.64 mm, 99.995% trace metals basis
Sigma-Aldrich
Copper, foil, thickness 1.0 mm, 99.999% trace metals basis
Continuous cast copper (O), BCR®, certified reference material, rod
Copper (S, P), BCR®, certified reference material, chips
Copper, IRMM®, certified reference material, 0.1 mm foil
Copper, IRMM®, certified reference material, 0.5 mm wire
Copper (O), BCR®, certified reference material, rod