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  • Transnitrosation of nitrosothiols: characterization of an elusive intermediate.

Transnitrosation of nitrosothiols: characterization of an elusive intermediate.

Journal of the American Chemical Society (2005-01-13)
Laura L Perissinotti, Adrián G Turjanski, Darío A Estrin, Fabio Doctorovich
PMID15643848
ABSTRACT

We report an investigation of the reaction between (S)-nitroso-l-cysteine ethyl ester and l-cysteine ethyl ester as a model of physiologically relevant transnitrosation processes. Our theoretical and experimental evidence clearly supports the existence of a nitroxyl disulfide intermediate in solution.