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  • Serine-type carboxypeptidase KexA of Aspergillus oryzae has broader substrate specificity than Saccharomyces cerevisiae Kex1 and is required for normal hyphal growth and conidiation.

Serine-type carboxypeptidase KexA of Aspergillus oryzae has broader substrate specificity than Saccharomyces cerevisiae Kex1 and is required for normal hyphal growth and conidiation.

Applied and environmental microbiology (2012-09-11)
Hiroto Morita, Sayako Tomita, Hiroshi Maeda, Ayako Okamoto, Youhei Yamagata, Ken-Ichi Kusumoto, Hitoshi Amano, Hiroki Ishida, Michio Takeuchi
PMID22961905
ABSTRACT

Aspergillus oryzae has an ortholog of Saccharomyces cerevisiae KEX1, termed kexA. A truncated form of KexA protein showed serine-type carboxypeptidase activity and somewhat broader substrate specificity than Kex1 protease. Furthermore, our results indicated that KexA is required for normal growth of A. oryzae and that it might be involved in hyphal branching.