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Merck

Visualizing nanoparticle mobility in liquid at atomic resolution.

Chemical communications (Cambridge, England) (2013-03-06)
Madeline J Dukes, Benjamin W Jacobs, David G Morgan, Harshad Hegde, Deborah F Kelly
ABSTRACT

Gold nanorods are widely known for their photothermal properties to treat solid tumors. Our work demonstrates the unrealized capacity to image these reagents in liquid at high resolution using Transmission Electron Microscopy (TEM). Here we perform the first atomic measurements of functionalized nanorods in solution while visualizing their dynamic behaviour with TEM.