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Metabolism of quercetin by Cunninghamella elegans ATCC 9245.

Journal of bioscience and bioengineering (2011-07-12)
Jiachen Zi, Jonathan Valiente, Jia Zeng, Jixun Zhan
ABSTRACT

Incubation of quercetin with Cunninghamella elegans ATCC 9245 yielded three metabolites, including quercetin 3-O-β-D-glucopyranoside, kaempferol 3-O-β-D-glucopyranoside and isorhamnetin 3-O-β-D-glucopyranoside. Glucosylation, O-methylation and dehydroxylation were involved in the process, among which dehydroxylation has never been found in Cunninghamella. Quercetin was completely metabolized in 72 h.