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  • Solvent and temperature effects on the conformational equilibria of a dihydrobenzo[h]quinolinium fluoroborate.

Solvent and temperature effects on the conformational equilibria of a dihydrobenzo[h]quinolinium fluoroborate.

Magnetic resonance in chemistry : MRC (2009-04-01)
Marcos Caroli Rezende, Juan Guerrero
ABSTRACT

Spectra of the N-phenyl-5,6-dihydro-2,4-diphenylbenzo[h]quinolinium tetrafluoroborate (1) and of the N-phenyl-5,6,8,9-tetrahydro-7-phenyldibenzo[c,h]acridinium tetrafluoroborate (2) were recorded in various solvents and temperatures. The analysis of the (1)H-NMR spectra of the tetrafluoroborate salt 1, recorded in acetone, acetonitrile, 1,1,2,2-tetrachloroethane and chloroform, revealed the existence of an equilibrium between two conformers in solution. Tight ion-pairing in chloroform led to a smaller barrier for interconversion between the two conformers. In more polar solvents, where the dihydrobenzoquinolinium exists as a free cation, theoretical calculations predicted larger barriers. The spectra of 1 in 1,1,2,2-tetrachloroethane also varied with temperature, resembling at higher temperatures the spectrum in CDCl(3) and at 300K spectra in more polar media. Spectra of 2 did not vary with the solvent or the temperature, in an indication of a much higher barrier to conformational interconversion, because of a greater steric hindrance between the N-phenyl substituent and the dihydrobenzo rings.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
1,1,2,2-Tetrachloroethane, reagent grade, ≥98%