- [Reaction of pyridinium salts with active methylene compounds].
[Reaction of pyridinium salts with active methylene compounds].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan (2006-02-08)
Reiko Fujita, Masato Hoshino, Yasuhiro Nishiuchi, Hiroshi Tomisawa
PMID16462100
ABSTRACT
The carbon-carbon bond-forming reactions of 1-methyl-2-methylthiophenylpyridinium iodides with active methylene compounds (such as dimethyl malonate, malononitrile) using NaH as a base gave the 2-substituted methylene-1,2-dihydropyridine derivatives.
MATERIALS