- Application of reinecke salt and alizarin S for the determination of promazine.
Application of reinecke salt and alizarin S for the determination of promazine.
Journal of pharmaceutical and biomedical analysis (2001-07-14)
H Puzanowska-Tarasiewicz, L Kuźmicka, E Kleszczewska
PMID11451636
ABSTRACT
Reinecke salt and alizarin S have been tested as reagents for the determination of promazine. They react in neutral and acidic media with promazine forming a reddish and brown crystalline compounds. The compounds are sparingly soluble in water but fairly soluble in acetone and methanol. The quantitative extraction of compound of promazine with alizarin S has been used for the extractive spectrophotometric determination of promazine. Formation of promazine ion-association complex with Reinecke salt has been applied for indirect determination of low concentrations of promazine by AAS measurement of the chromium content of the reineckate counter - anion.
MATERIALS