- Glycosylation of l,4:3,6-dianhydro-D-glucitol (isosorbide).
Glycosylation of l,4:3,6-dianhydro-D-glucitol (isosorbide).
Carbohydrate research (2004-09-25)
David J Claffey, Mary F Casey, Patrick A Finan
PMID15388358
ABSTRACT
Condensation of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-, 2,3,4-tri-O-acetyl-alpha-D-xylopyranosyl- and of 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosyl bromides with l,4:3,6-dianhydro-D-glucitol under Koenigs-Knorr conditions, and using the Helferich modification of the reaction showed regioselectivity in glysosylation at C-5 of isosorbide.