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Glycobiology Profiling Tools

N-glycan structure with a wrench attached. Glycobiology profiling tools to support glycoprotein analysis, prep, modification and other glycobiology workflow needs.

Glycobiology profiling is critical to many areas of research. For example, glycosylation is one of the most common and impactful modifications found in biologic systems.  It is seen in the simplest of prokaryotes and the most complex multicellular organisms, attached to proteins, lipids, and even RNA playing roles in structure, function, and regulation.  As the knowledge base and methods evolve, scientists need the right tools for the job.  We are filling your toolbox with glycobiology reagents and tools like enzymes, resins, labels, and reagents to aid in the discovery and experimentation around glycobiology.

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Glycobiology Profiling Categories

To accommodate your glycobiology workflow needs, we offer a wide range of products for functional and structural analysis of glycans, including glycoprocessing and glycosylation enzymes, glycan labels, lectins, capture resins, standards, glycoproteins, and free oligosaccharides. This includes offerings of carbohydrate-recognizing proteins such as lectins and galectins, carbohydrate-active enzymes like glycosidases (exoglycosidases, endoglycosidases), and glycosyltransferases. Additionally, our GlycoProfile™ kits are a curated product line that have been developed to simplify common workflows including release and labeling of N-linked and O-linked glycans.

The glycobiology profiling tools we offer can be broken into these 4 categories:

Capture step of glycobiology workflow where enzyme is attaching to glycan structures.

CAPTURE

Release step of glycobiology workflow with a depiction of N-glycans and O-glycan structures.

RELEASE

Modify step of glycobiology workflow with a depiction of modifying glycan structures. Erlenmeyer flask in the middle of a circular process workflow with glycans linked to the left and glycans broken apart on the right.

MODIFY

Analyze step of glycobiology workflow with a depiction of N-linked glycan structures that are tagged with labels for analyzing.

ANALYZE

Related Resources

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Related Applications
Glycobiology
Glycobiology studies the structure, biosynthesis, biology, and evolution of carbohydrates, or glycans, and how disorders in these processes play a role in diseases, in order to develop glyocotherapeutics.
Western Blotting
An overview of the principles and applications of Western blotting for protein detection. Includes links to detailed protocols, videos, and other resources for protein extraction, gel electrophoresis, transfer to PVDF or nitrocellulose membranes, and chemiluminescent, colorimetric, and fluorescent detection methods.
Protein Labeling & Modification
Protein labeling applications using enzyme-protein labeling, fluorescent protein labeling, and targeted protein degradation technologies.
Protein Purification
Protein purification techniques, reagents, and protocols for purifying recombinant proteins using methods including, ion-exchange, size-exclusion, and protein affinity chromatography.
Protein Structural Analysis
Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.
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