861448
8-Azaguanine
98%
Synonym(s):
2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo
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About This Item
Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
Beilstein:
171098
EC Number:
MDL number:
UNSPSC Code:
12352200
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Assay
98%
mp
>300 °C (lit.)
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
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Y Xiao et al.
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 22(2), 113-115 (1997-01-01)
A human lung cancer cell line (A549) mutant with hypoxanthine guanine phosphoribosyltransferase (HGPRT) deficiency and resistance to 8-AG was established by treatment of the A549 cells with 3 micrograms.ml-1 N-methyl-N'-nitro-nitrosoguanidine (MNNG), and prescreened in 0.25% agarose DMEM semisolid medium containing
F R Ridzlan et al.
Tropical biomedicine, 27(3), 632-638 (2011-03-15)
Leptospirosis is recognized as one of the important zoonotic diseases in the world including Malaysia. A total of 145 soil and water samples were collected from selected National Service Training Centres (NSTC) in Kelantan and Terengganu. The samples were inoculated
Bashir Mir et al.
Nucleic acids research, 32(3), e25-e25 (2004-02-13)
The use of primary somatic cells in nuclear transfer procedure has opened a new opportunity to manipulate domestic animal genomes via homologous recombination. To date, while a few loci have been targeted in somatic cells using similar enrichment strategies as
Christian Pfeifle et al.
Anticancer research, 29(11), 4489-4496 (2009-12-25)
Despite improvements in the treatment of patients with Ewing family tumours (EFT) during the past decades, the prognosis for patients with advanced disease is still unsatisfying. New treatment strategies have to be developed. A hypoxanthine/aminopterin/thymidine (HAT)-sensitive EFT cell line was
Jacek Wierzchowski et al.
Nucleosides, nucleotides & nucleic acids, 24(5-7), 459-464 (2005-10-27)
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, an excellent fluorescent/fluorogenic substrate for the synthetic pathway of the reaction, and its 9-(2-phosphonylmethoxyethyl) derivative, a bisubstrate analogue inhibitor, were carried out. The goal was to
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