YTHDF2
YTH domain family, member 2
Synonyms:
HGRG8, NY-REN-2
Species:
Human YTHDF2 (51441), Mouse Ythdf2 (213541), Rat Ythdf2 (313053), cow YTHDF2 (541050), dog YTHDF2 (478161), Domestic Rabbit YTHDF2 (100351518), domestic guinea pig Ythdf2 (100733512), domestic cat YTHDF2 (101088596), chicken YTHDF2 (419583), naked mole-rat Ythdf2 (101721610)
UniProtKB ID:
Gene ID:
- Human(51441) Summary: This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
- Mouse(213541) YTH domain family 2
- Rat(313053) YTH domain family, member 2
- cow(541050) YTH domain family, member 2
- dog(478161) YTH domain family, member 2
- Domestic Rabbit(100351518) YTH domain family, member 2
- domestic guinea pig(100733512) YTH domain family, member 2
- domestic cat(101088596) YTH domain family, member 2
- chicken(419583) YTH domain family, member 2
- naked mole-rat(101721610) YTH domain family, member 2
- sheep(101122840) YTH domain family, member 2
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