VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
Synonyms:
SKD1, SKD1B, VPS4-2
Species:
Human VPS4B (9525), Mouse Vps4b (20479), Rat Vps4b (360834), sheep VPS4B (101103111), naked mole-rat Vps4b (101702359), domestic cat VPS4B (101083116), Domestic Rabbit VPS4B (100338152), dog VPS4B (607306), cow VPS4B (539357), dog VPS4B (476178) ...More
UniProtKB ID:
Gene ID:
- Human(9525) Summary: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008]
- Mouse(20479) vacuolar protein sorting 4b (yeast)
- Rat(360834) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- sheep(101103111) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- naked mole-rat(101702359) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- domestic cat(101083116) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- Domestic Rabbit(100338152) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- dog(607306) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- cow(539357) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- dog(476178) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- Zebrafish(393880) vacuolar protein sorting 4b (yeast)
- domestic guinea pig(100730380) vacuolar protein sorting 4 homolog B (S. cerevisiae)
- chicken(420901) vacuolar protein sorting 4 homolog B (S. cerevisiae)
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