UBE2D3
ubiquitin-conjugating enzyme E2D 3
Synonyms:
E2(17)KB3, UBC4/5, UBCH5C
Species:
Human UBE2D3 (7323), Mouse Ube2d3 (66105), Rat Ube2d3 (81920), domestic cat UBE2D3 (101094845), chicken UBE2D3 (422713), Zebrafish ube2d3 (321832), domestic guinea pig Ube2d3 (100730907), naked mole-rat Ube2d3 (101725641), cow UBE2D3 (326583), sheep UBE2D3 (101107195)
UniProtKB ID:
Gene ID:
- Human(7323) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(66105) ubiquitin-conjugating enzyme E2D 3
- Rat(81920) ubiquitin-conjugating enzyme E2D 3
- domestic cat(101094845) ubiquitin-conjugating enzyme E2D 3
- chicken(422713) ubiquitin-conjugating enzyme E2D 3
- Zebrafish(321832) ubiquitin-conjugating enzyme E2D 3
- domestic guinea pig(100730907) ubiquitin-conjugating enzyme E2D 3
- naked mole-rat(101725641) ubiquitin-conjugating enzyme E2D 3
- cow(326583) ubiquitin-conjugating enzyme E2D 3
- sheep(101107195) ubiquitin-conjugating enzyme E2D 3
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