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Merck

UBE2C

ubiquitin-conjugating enzyme E2C

Synonyms:
UBCH10, dJ447F3.2
Species:
UniProtKB ID:
Gene ID:
  • Human(11065) Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
  • Mouse(68612) ubiquitin-conjugating enzyme E2C
  • Rat(296368) ubiquitin-conjugating enzyme E2C
  • dog(485898) ubiquitin-conjugating enzyme E2C
  • Zebrafish(566441) ubiquitin-conjugating enzyme E2C
  • chicken(100859413) ubiquitin-conjugating enzyme E2C
  • domestic guinea pig(100718665) ubiquitin-conjugating enzyme E2C
  • naked mole-rat(101724369) ubiquitin-conjugating enzyme E2C
  • domestic cat(101087052) ubiquitin-conjugating enzyme E2C
  • Horse(100056334) ubiquitin-conjugating enzyme E2C
  • cow(506962) ubiquitin-conjugating enzyme E2C
  • sheep(101115053) ubiquitin-conjugating enzyme E2C

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