TSPAN6
tetraspanin 6
Synonyms:
T245, TM4SF6, TSPAN-6
Species:
Human TSPAN6 (7105), Mouse Tspan6 (56496), Rat Tspan6 (302313), naked mole-rat Tspan6 (101721505), domestic guinea pig Tspan6 (100717838), sheep TSPAN6 (101110392), cow TSPAN6 (514741), dog TSPAN6 (480981), domestic cat TSPAN6 (101085355), chicken TSPAN6 (422262)
UniProtKB ID:
Gene ID:
- Human(7105) Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
- Mouse(56496) tetraspanin 6
- Rat(302313) tetraspanin 6
- naked mole-rat(101721505) tetraspanin 6
- domestic guinea pig(100717838) tetraspanin 6
- sheep(101110392) tetraspanin 6
- cow(514741) tetraspanin 6
- dog(480981) tetraspanin 6
- domestic cat(101085355) tetraspanin 6
- chicken(422262) tetraspanin 6
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