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Merck

TRIM25

tripartite motif containing 25

Synonyms:
EFP, RNF147, Z147, ZNF147
Species:
Human TRIM25 (7706), Mouse Trim25 (217069), Rat Trim25 (494338), domestic guinea pig Trim25 (100727761), naked mole-rat Trim25 (101710143), Zebrafish trim25 (393144), chicken TRIM25 (417401), dog TRIM25 (491103), Horse TRIM25 (100146440), domestic cat TRIM25 (101084663) ...More
UniProtKB ID:
Q14258
Gene ID:
  • Human(7706) Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008]
  • Mouse(217069) tripartite motif-containing 25
  • Rat(494338) tripartite motif-containing 25
  • domestic guinea pig(100727761) tripartite motif containing 25
  • naked mole-rat(101710143) tripartite motif containing 25
  • Zebrafish(393144) tripartite motif-containing 25
  • chicken(417401) tripartite motif containing 25
  • dog(491103) tripartite motif containing 25
  • Horse(100146440) tripartite motif containing 25
  • domestic cat(101084663) tripartite motif containing 25
  • cow(510923) tripartite motif containing 25
  • sheep(101122873) tripartite motif containing 25

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