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Merck

TREM2

triggering receptor expressed on myeloid cells 2

Synonyms:
TREM-2, Trem2a, Trem2b, Trem2c
Species:
UniProtKB ID:
Gene ID:
  • Human(54209) Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
  • Mouse(83433) triggering receptor expressed on myeloid cells 2
  • Rat(301227) triggering receptor expressed on myeloid cells 2
  • sheep(101105447) triggering receptor expressed on myeloid cells 2
  • cow(506467) triggering receptor expressed on myeloid cells 2
  • domestic cat(101099297) triggering receptor expressed on myeloid cells 2
  • dog(608965) triggering receptor expressed on myeloid cells 2
  • chicken(419920) triggering receptor expressed on myeloid cells 2
  • naked mole-rat(101717064) triggering receptor expressed on myeloid cells 2
  • domestic guinea pig(100720722) triggering receptor expressed on myeloid cells 2

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human TREM-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human