TOP3B
topoisomerase (DNA) III beta
Synonyms:
TOP3B1
Species:
Human TOP3B (8940), Mouse Top3b (21976), Rat Top3b (287930), cow TOP3B (537418), sheep TOP3B (101114728), domestic cat TOP3B (101088117), Horse TOP3B (100051153), dog TOP3B (477576), chicken TOP3B (416771), naked mole-rat Top3b (101708161) ...More
UniProtKB ID:
Gene ID:
- Human(8940) Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
- Mouse(21976) topoisomerase (DNA) III beta
- Rat(287930) topoisomerase (DNA) III beta
- cow(537418) topoisomerase (DNA) III beta
- sheep(101114728) topoisomerase (DNA) III beta
- domestic cat(101088117) topoisomerase (DNA) III beta
- Horse(100051153) topoisomerase (DNA) III beta
- dog(477576) topoisomerase (DNA) III beta
- chicken(416771) topoisomerase (DNA) III beta
- naked mole-rat(101708161) topoisomerase (DNA) III beta
- domestic guinea pig(100734860) topoisomerase (DNA) III beta
- Domestic Rabbit(100345272) topoisomerase (DNA) III beta
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