TNNI3
troponin I type 3 (cardiac)
Synonyms:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Species:
Human TNNI3 (7137), Mouse Tnni3 (21954), Rat Tnni3 (29248), Horse TNNI3 (100034065), sheep TNNI3 (101121961), domestic guinea pig Tnni3 (100718375), naked mole-rat Tnni3 (101711288), chicken TNNI3 (396428), dog TNNI3 (403566), domestic cat TNNI3 (493744)
UniProtKB ID:
Gene ID:
- Human(7137) Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
- Mouse(21954) troponin I, cardiac 3
- Rat(29248) troponin I type 3 (cardiac)
- Horse(100034065) troponin I type 3 (cardiac)
- sheep(101121961) troponin I type 3 (cardiac)
- domestic guinea pig(100718375) troponin I type 3 (cardiac)
- naked mole-rat(101711288) troponin I type 3 (cardiac)
- chicken(396428) troponin I type 3 (cardiac)
- dog(403566) troponin I type 3 (cardiac)
- domestic cat(493744) troponin I type 3 (cardiac)
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