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Merck

TIMP1

TIMP metallopeptidase inhibitor 1

Synonyms:
CLGI, EPA, EPO, HCI, TIMP
Species:
UniProtKB ID:
Gene ID:
  • Human(7076) Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
  • Mouse(21857) tissue inhibitor of metalloproteinase 1
  • Rat(116510) TIMP metallopeptidase inhibitor 1
  • domestic cat(101095886) TIMP metallopeptidase inhibitor 1
  • naked mole-rat(101722238) TIMP metallopeptidase inhibitor 1
  • dog(403816) TIMP metallopeptidase inhibitor 1
  • cow(282092) TIMP metallopeptidase inhibitor 1
  • domestic guinea pig(101787552) TIMP metallopeptidase inhibitor 1
  • sheep(443331) TIMP metallopeptidase inhibitor 1
  • Horse(100034220) TIMP metallopeptidase inhibitor 1

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rhesus Macaque TIMP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
Porcine TIMP1 / Metalloproteinase Inhibitor 1 ELISA Kit, ,
Species
Human TIMP-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Rat TIMP-1 ELISA Kit, for cell and tissue lysates,
Species
rat
Mouse TIMP-1 ELISA Kit, for cell and tissue lysates,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TIMP-1 Antibody, clone 147-6D11, clone 147-6D11, Chemicon®, from mouse,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-TIMP-1 Antibody, clone 102D1, clone 102D1, Chemicon®, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-TIMP-1 Antibody, clone 7-6C1, clone 7-6C1, Chemicon®, from mouse,
Species Reactivity
bovine, human, rat
Application
ELISA
immunohistochemistry

western blot
Anti-TIMP-1 Antibody, Chemicon®, from rabbit,
Species Reactivity
bovine, ferret, horse, rabbit, rat, sheep
Application
ELISA
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
TIMP-1, recombinant, active human, ,
Species
human