TIGIT
T cell immunoreceptor with Ig and ITIM domains
Synonyms:
VSIG9, VSTM3, WUCAM
Species:
Human TIGIT (201633), Mouse Tigit (100043314), Rat Tigit (363784), naked mole-rat Tigit (101713509), domestic guinea pig Tigit (100716636), domestic cat TIGIT (101098326), dog TIGIT (487986), cow TIGIT (100140801), sheep TIGIT (101116533)
UniProtKB ID:
Gene ID:
- Human(201633) Summary: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
- Mouse(100043314) T cell immunoreceptor with Ig and ITIM domains
- Rat(363784) T cell immunoreceptor with Ig and ITIM domains
- naked mole-rat(101713509) T cell immunoreceptor with Ig and ITIM domains
- domestic guinea pig(100716636) T cell immunoreceptor with Ig and ITIM domains
- domestic cat(101098326) T cell immunoreceptor with Ig and ITIM domains
- dog(487986) T cell immunoreceptor with Ig and ITIM domains
- cow(100140801) T cell immunoreceptor with Ig and ITIM domains
- sheep(101116533) T cell immunoreceptor with Ig and ITIM domains
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